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Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U

TDP-43 is a multifunctional DNA/RNA-binding factor that has been implicated in the regulation of neuronal plasticity. TDP-43 has also been identified as the major constituent of the neuronal cytoplasmic inclusions (NCIs) that are characteristic of a range of neurodegenerative diseases, including the...

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Detalles Bibliográficos
Autores principales:	Tsai, Kuen-Jer, Yang, Chun-Hung, Fang, Yen-Hsin, Cho, Kuan-Hung, Chien, Wei-Lin, Wang, Wei-Ting, Wu, Tzu-Wei, Lin, Ching-Po, Fu, Wen-Mei, Shen, Che-Kun James
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916125/ https://www.ncbi.nlm.nih.gov/pubmed/20660618 http://dx.doi.org/10.1084/jem.20092164

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