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Exploitation of conserved eukaryotic host cell farnesylation machinery by an F-box effector of Legionella pneumophila
Farnesylation involves covalent linkage of eukaryotic proteins to a lipid moiety to anchor them into membranes, which is essential for the biological function of Ras and other proteins. A large cadre of bacterial effectors is injected into host cells by intravacuolar pathogens through elaborate type...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916131/ https://www.ncbi.nlm.nih.gov/pubmed/20660614 http://dx.doi.org/10.1084/jem.20100771 |