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Exploitation of conserved eukaryotic host cell farnesylation machinery by an F-box effector of Legionella pneumophila

Farnesylation involves covalent linkage of eukaryotic proteins to a lipid moiety to anchor them into membranes, which is essential for the biological function of Ras and other proteins. A large cadre of bacterial effectors is injected into host cells by intravacuolar pathogens through elaborate type...

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Detalles Bibliográficos
Autores principales: Price, Christopher T.D., Al-Quadan, Tasneem, Santic, Marina, Jones, Snake C., Abu Kwaik, Yousef
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916131/
https://www.ncbi.nlm.nih.gov/pubmed/20660614
http://dx.doi.org/10.1084/jem.20100771

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