Cargando…

Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice

The protease a disintegrin and metalloprotease (ADAM) 17 cleaves tumor necrosis factor (TNF), L-selectin, and epidermal growth factor receptor (EGF-R) ligands from the plasma membrane. ADAM17 is expressed in most tissues and is up-regulated during inflammation and cancer. ADAM17-deficient mice are n...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chalaris, Athena, Adam, Nina, Sina, Christian, Rosenstiel, Philip, Lehmann-Koch, Judith, Schirmacher, Peter, Hartmann, Dieter, Cichy, Joanna, Gavrilova, Olga, Schreiber, Stefan, Jostock, Thomas, Matthews, Vance, Häsler, Robert, Becker, Christoph, Neurath, Markus F., Reiß, Karina, Saftig, Paul, Scheller, Jürgen, Rose-John, Stefan
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916135/ https://www.ncbi.nlm.nih.gov/pubmed/20603312 http://dx.doi.org/10.1084/jem.20092366

Ejemplares similares

A Disintegrin and Metalloprotease (ADAM): Historical Overview of Their Functions
por: Giebeler, Nives, et al.
Publicado: (2016)

A Disintegrin and Metalloproteases (ADAMs): Activation, Regulation and Mechanisms of Catalysis
por: Maretzky, Thorsten
Publicado: (2021)

A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of murine liver tissue homeostasis
por: Müller, Miryam, et al.
Publicado: (2016)

The Disintegrin and Metalloprotease ADAM12 Is Associated with TGF-β-Induced Epithelial to Mesenchymal Transition
por: Ruff, Michaël, et al.
Publicado: (2015)

Identification of ILK as a new partner of the ADAM12 disintegrin and metalloprotease in cell adhesion and survival
por: Leyme, Anthony, et al.
Publicado: (2012)

Critical Role of the Disintegrin Metalloprotease ADAM-like Decysin-1 [ADAMDEC1] for Intestinal Immunity and Inflammation
por: O’Shea, Nuala R., et al.
Publicado: (2016)

Expression of a disintegrin and metalloprotease (ADAM and ADAMTS) enzymes in human non-small-cell lung carcinomas (NSCLC)
por: Rocks, N, et al.
Publicado: (2006)

Identification of SH3 Domain Proteins Interacting with the Cytoplasmic Tail of the A Disintegrin and Metalloprotease 10 (ADAM10)
por: Ebsen, Henriette, et al.
Publicado: (2014)

Metalloprotease-disintegrin ADAM12 actively promotes the stem cell-like phenotype in claudin-low breast cancer
por: Duhachek-Muggy, Sara, et al.
Publicado: (2017)

The role of polymorphisms in ADAM33, a disintegrin and metalloprotease 33, in childhood asthma and lung function in two German populations
por: Schedel, Michaela, et al.
Publicado: (2006)

The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10
por: Jefferson, Tamara, et al.
Publicado: (2012)

Regulation of A disintegrin and metalloproteinase (ADAM) family sheddases ADAM10 and ADAM17: The emerging role of tetraspanins and rhomboids
por: Matthews, Alexandra L., et al.
Publicado: (2017)

A Disintegrin and Metalloprotease 17 in the Cardiovascular and Central Nervous Systems
por: Xu, Jiaxi, et al.
Publicado: (2016)

Effect of type 2 diabetes on A disintegrin and metalloprotease 10
por: Lam, Sum, et al.
Publicado: (2022)

ADAM metalloproteases and EGFR signalling
por: Gee, Julia MW, et al.
Publicado: (2003)

Tetraspanin 8 Subfamily Members Regulate Substrate-Specificity of a Disintegrin and Metalloprotease 17
por: Müller, Miryam, et al.
Publicado: (2022)

ADAM, a novel family of membrane proteins containing A Disintegrin And Metalloprotease domain: multipotential functions in cell-cell and cell- matrix interactions
Publicado: (1995)

ADAM-15 Disintegrin-Like Domain Structure and Function
por: Lu, Dong, et al.
Publicado: (2010)

Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function
por: Kuhn, Peer-Hendrik, et al.
Publicado: (2016)

The disintegrin-metalloproteinases ADAM10 and ADAM17 are upregulated in cutaneous squamous cell carcinomas
por: Oh, S.-T., et al.
Publicado: (2016)

TspanC8 Tetraspanins and A Disintegrin and Metalloprotease 10 (ADAM10) Interact via Their Extracellular Regions: EVIDENCE FOR DISTINCT BINDING MECHANISMS FOR DIFFERENT TspanC8 PROTEINS
por: Noy, Peter J., et al.
Publicado: (2016)

A Disintegrin and Metalloprotease 10 in neuronal maturation and gliogenesis during cortex development
por: Ma, Zhixing, et al.
Publicado: (2013)

Novel Approaches and Challenges of Discovery of Exosite Modulators of a Disintegrin and Metalloprotease 10
por: Minond, Dmitriy
Publicado: (2020)

The Metalloprotease-Disintegrin ADAM8 Alters the Tumor Suppressor miR-181a-5p Expression Profile in Glioblastoma Thereby Contributing to Its Aggressiveness
por: Schäfer, Agnes, et al.
Publicado: (2022)

Analysis of A Disintegrin and Metalloprotease 17 (ADAM17) Expression as a Prognostic Marker in Ovarian Cancer Patients Undergoing First-Line Treatment Plus Bevacizumab
por: Fabbi, Marina, et al.
Publicado: (2022)

Molecular switch in human diseases-disintegrin and metalloproteinases, ADAM17
por: Yang, Guang, et al.
Publicado: (2021)

Lack of a-disintegrin-and-metalloproteinase ADAM10 leads to intracellular accumulation and loss of shedding of the cellular prion protein in vivo
por: Altmeppen, Hermann C, et al.
Publicado: (2011)

Biomarker to distinguish hepatocellular carcinoma from cholangiocarcinoma by serum a disintegrin and metalloprotease 12
por: Daduang, Jureerut, et al.
Publicado: (2011)

Identification of novel substrates of a disintegrin and metalloprotease 17 by specific labeling of surface proteins
por: Omoteyama, Kazuki, et al.
Publicado: (2020)

Deficiency of the Metalloproteinase-Disintegrin ADAM8 Is Associated with Thymic Hyper-Cellularity
por: Gossens, Klaus, et al.
Publicado: (2010)

A-Disintegrin and Metalloproteinase (ADAM) 17 Enzymatically Degrades Interferon-gamma
por: Kanzaki, Hiroyuki, et al.
Publicado: (2016)

Expression of A disintegrin and metalloprotease 8 is associated with cell growth and poor survival in colorectal cancer
por: Yang, Zuli, et al.
Publicado: (2014)

Redundancy of protein disulfide isomerases in the catalysis of the inactivating disulfide switch in A Disintegrin and Metalloprotease 17
por: Krossa, Sebastian, et al.
Publicado: (2018)

A Disintegrin and Metalloprotease 12 Promotes Tumor Progression by Inhibiting Apoptosis in Human Colorectal Cancer
por: Park, Young-Lan, et al.
Publicado: (2021)

A Disintegrin and Metalloprotease 10 Expressions Modulate Potential Metastatic and Thrombus Formation in Pancreatic Carcinoma
por: Yu, Miao, et al.
Publicado: (2022)

A disintegrin and metalloprotease 12 contributes to colorectal cancer metastasis by regulating epithelial-mesenchymal transition
por: Oh, Hyung-Hoon, et al.
Publicado: (2023)

Knockdown of a disintegrin A metalloprotease 12 (ADAM12) during adipogenesis reduces cell numbers, delays differentiation, and increases lipid accumulation in 3T3-L1 cells
por: Coles, Chantal A., et al.
Publicado: (2018)

Phenotypic Diversity of Breast Cancer-Related Mutations in Metalloproteinase-Disintegrin ADAM12
por: Qi, Yue, et al.
Publicado: (2014)

Inhibition of the extracellular enzyme A disintegrin and metalloprotease with thrombospondin motif 4 prevents cardiac fibrosis and dysfunction
por: Vistnes, Maria, et al.
Publicado: (2023)

Retraction: miR-126a-3p induces proliferation, migration and invasion of trophoblast cells in preeclampsia-like rats through inhibiting a disintegrin and metalloprotease 9(ADAM9)
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_89r0q8s0e5c5b5oi669kv55gg8