Dual Beneficial Effects of (-)-Epigallocatechin-3-Gallate on Levodopa Methylation and Hippocampal Neurodegeneration: In Vitro and In Vivo Studies

BACKGROUND: A combination of levodopa (L-DOPA) and carbidopa is the most commonly-used treatment for symptom management in Parkinson's disease. Studies have shown that concomitant use of a COMT inhibitor is highly beneficial in controlling the wearing-off phenomenon by improving L-DOPA bioavail...

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Detalles Bibliográficos
Autores principales: Kang, Ki Sung, Wen, Yujing, Yamabe, Noriko, Fukui, Masayuki, Bishop, Stephanie C., Zhu, Bao Ting
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916818/
https://www.ncbi.nlm.nih.gov/pubmed/20700524
http://dx.doi.org/10.1371/journal.pone.0011951

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