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Incorporating tumour pathology information into breast cancer risk prediction algorithms

INTRODUCTION: Mutations in BRCA1 and BRCA2 confer high risks of breast cancer and ovarian cancer. The risk prediction algorithm BOADICEA (Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm) may be used to compute the probabilities of carrying mutations in BRCA1 and BRC...

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Detalles Bibliográficos
Autores principales: Mavaddat, Nasim, Rebbeck, Timothy R, Lakhani, Sunil R, Easton, Douglas F, Antoniou, Antonis C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917017/
https://www.ncbi.nlm.nih.gov/pubmed/20482762
http://dx.doi.org/10.1186/bcr2576