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Novel design principles enable specific targeting of imaging and therapeutic agents to necrotic domains in breast tumors
INTRODUCTION: Necrosis at the tumor center is a common feature of aggressive breast cancers and has been associated with poor prognosis. It is commonly identified by means of invasive histopathology, which often correlates with morbidity and potential tumor cell dissemination, and limits the reconst...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917020/ https://www.ncbi.nlm.nih.gov/pubmed/20497549 http://dx.doi.org/10.1186/bcr2579 |