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Progesterone reverses the mesenchymal phenotypes of basal phenotype breast cancer cells via a membrane progesterone receptor mediated pathway

INTRODUCTION: Basal phenotype breast cancers (BPBC) are often associated with apparent epithelial to mesenchymal transition (EMT). The role of progesterone (P4) in regulating EMT of BPBC has not been reported. METHODS: The EMT relevant biology was investigated in vitro using human BPBC cell models (...

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Detalles Bibliográficos
Autores principales: Zuo, Lian, Li, Wei, You, Shaojin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917029/
https://www.ncbi.nlm.nih.gov/pubmed/20540763
http://dx.doi.org/10.1186/bcr2588