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Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer

INTRODUCTION: Accumulating evidence suggests that both levels and activity of the estrogen receptor (ER) and the progesterone receptor (PR) are dramatically influenced by growth-factor receptor (GFR) signaling pathways, and that this crosstalk is a major determinant of both breast cancer progression...

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Detalles Bibliográficos
Autores principales:	Creighton, Chad J, Fu, Xiaoyong, Hennessy, Bryan T, Casa, Angelo J, Zhang, Yiqun, Gonzalez-Angulo, Ana Maria, Lluch, Ana, Gray, Joe W, Brown, Powell H, Hilsenbeck, Susan G, Osborne, C Kent, Mills, Gordon B, Lee, Adrian V, Schiff, Rachel
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917035/ https://www.ncbi.nlm.nih.gov/pubmed/20569503 http://dx.doi.org/10.1186/bcr2594

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