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RNA interference (RNAi) screening approach identifies agents that enhance paclitaxel activity in breast cancer cells

INTRODUCTION: Paclitaxel is a widely used drug in the treatment of patients with locally advanced and metastatic breast cancer. However, only a small portion of patients have a complete response to paclitaxel-based chemotherapy, and many patients are resistant. Strategies that increase sensitivity a...

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Detalles Bibliográficos
Autores principales: Bauer, Joshua A, Ye, Fei, Marshall, Clayton B, Lehmann, Brian D, Pendleton, Christopher S, Shyr, Yu, Arteaga, Carlos L, Pietenpol, Jennifer A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917036/
https://www.ncbi.nlm.nih.gov/pubmed/20576088
http://dx.doi.org/10.1186/bcr2595

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