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NK Cell Terminal Differentiation: Correlated Stepwise Decrease of NKG2A and Acquisition of KIRs

BACKGROUND: Terminal differentiation of NK cells is crucial in maintaining broad responsiveness to pathogens and discriminating normal cells from cells in distress. Although it is well established that KIRs, in conjunction with NKG2A, play a major role in the NK cell education that determines whethe...

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Detalles Bibliográficos
Autores principales: Béziat, Vivien, Descours, Benjamin, Parizot, Christophe, Debré, Patrice, Vieillard, Vincent
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917352/
https://www.ncbi.nlm.nih.gov/pubmed/20700504
http://dx.doi.org/10.1371/journal.pone.0011966