Evidence for Sub-Haplogroup H5 of Mitochondrial DNA as a Risk Factor for Late Onset Alzheimer's Disease

BACKGROUND: Alzheimer's Disease (AD) is the most common neurodegenerative disease and the leading cause of dementia among senile subjects. It has been proposed that AD can be caused by defects in mitochondrial oxidative phosphorylation. Given the fundamental contribution of the mitochondrial ge...

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Detalles Bibliográficos
Autores principales: Santoro, Aurelia, Balbi, Valentina, Balducci, Elisa, Pirazzini, Chiara, Rosini, Francesca, Tavano, Francesca, Achilli, Alessandro, Siviero, Paola, Minicuci, Nadia, Bellavista, Elena, Mishto, Michele, Salvioli, Stefano, Marchegiani, Francesca, Cardelli, Maurizio, Olivieri, Fabiola, Nacmias, Benedetta, Chiamenti, Andrea Maria, Benussi, Luisa, Ghidoni, Roberta, Rose, Giuseppina, Gabelli, Carlo, Binetti, Giuliano, Sorbi, Sandro, Crepaldi, Gaetano, Passarino, Giuseppe, Torroni, Antonio, Franceschi, Claudio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917370/
https://www.ncbi.nlm.nih.gov/pubmed/20700462
http://dx.doi.org/10.1371/journal.pone.0012037

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