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Hypoxia inducible factor 1α gene (HIF-1α) splice variants: potential prognostic biomarkers in breast cancer

BACKGROUND: Hypoxia-inducible factor 1 (HIF-1) is a master transcriptional regulator of genes regulating oxygen homeostasis. The HIF-1 protein is composed of two HIF-1α and HIF-1β/aryl hydrocarbon receptor nuclear translocator (ARNT) subunits. The prognostic relevance of HIF-1α protein overexpressio...

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Detalles Bibliográficos
Autores principales:	Dales, Jean-Philippe, Beaufils, Nathalie, Silvy, Monique, Picard, Christophe, Pauly, Vanessa, Pradel, Vincent, Formisano-Tréziny, Christine, Bonnier, Pascal, Giusiano, Sophie, Charpin, Colette, Gabert, Jean
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917392/ https://www.ncbi.nlm.nih.gov/pubmed/20624301 http://dx.doi.org/10.1186/1741-7015-8-44

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