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Targeted gene therapy of nasopharyngeal cancer in vitro and in vivo by enhanced thymidine kinase expression driven by human TERT promoter and CMV enhancer

BACKGROUND/AIM: To explore the therapeutic effects of thymidine kinase (TK) expressed by enhanced vector pGL3-basic- hTERTp-TK-EGFP-CMV driven by human telomerase reverse transcriptase promoter (hTERTp) as well as cytomegalovirus immediate early promoter enhancer (CMV). MATERIALS/METHODS: Enhanced T...

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Detalles Bibliográficos
Autores principales:	Shen, Cong-Xiang, Wen, Zhong, Qian, Yu-Hong, Mu, Shao-Feng, Guan, Xiao-Fang
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917418/ https://www.ncbi.nlm.nih.gov/pubmed/20626878 http://dx.doi.org/10.1186/1756-9966-29-94

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