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1α,25-dihydroxyvitamin D(3) acts predominately in mature osteoblasts under conditions of high extracellular phosphate to increase fibroblast growth factor 23 production in vitro
Osteoblasts/osteocytes are the principle sources of fibroblast growth factor 23 (FGF23), a phosphaturic hormone, but the regulation of FGF23 expression during osteoblast development remains uncertain. Because 1α,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) and inorganic phosphate (Pi) may act as poten...
Autores principales: | Yamamoto, Ryoko, Minamizaki, Tomoko, Yoshiko, Yuji, Yoshioka, Hirotaka, Tanne, Kazuo, Aubin, Jane E, Maeda, Norihiko |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioScientifica
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917591/ https://www.ncbi.nlm.nih.gov/pubmed/20530653 http://dx.doi.org/10.1677/JOE-10-0058 |
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