Regulation of myeloid leukemia by the cell fate determinant Musashi

Chronic myelogenous leukemia (CML) can progress from an indolent chronic phase to an aggressive blast crisis phase1 but the molecular basis of this transition remains poorly understood. Here we have used mouse models of CML2,3 to show that disease progression is regulated by the Musashi-Numb signali...

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Detalles Bibliográficos
Autores principales: Ito, Takahiro, Kwon, Hyog Young, Zimdahl, Bryan, Congdon, Kendra L., Blum, Jordan, Lento, William E., Zhao, Chen, Lagoo, Anand, Gerrard, Gareth, Foroni, Letizia, Goldman, John, Goh, Harriet, Kim, Soo-Hyun, Kim, Dong-Wook, Chuah, Charles, Oehler, Vivian G., Radich, Jerald P., Jordan, Craig T., Reya, Tannishtha
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918284/
https://www.ncbi.nlm.nih.gov/pubmed/20639863
http://dx.doi.org/10.1038/nature09171

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