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Novel insights into K(+) selectivity from high resolution structures of an open K(+) channel pore
K(+) channels are highly selective for K(+) over Na(+). Here we present several crystal structures of the MthK K(+) channel pore at up to 1.45 Å resolution. The MthK selectivity filter maintains a conductive conformation even in the absence of K(+), allowing the channel to conduct Na(+). The high re...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918291/ https://www.ncbi.nlm.nih.gov/pubmed/20676101 http://dx.doi.org/10.1038/nsmb.1865 |