Syndrome of inappropriate ADH secretion (SIADH) associated with citalopram use

Selective serotonin reuptake inhibitors (SSRIs) can cause the syndrome of inappropriate antidiuretic hormone secretion (SIADH). SIADH is associated with hyponatraemia without oedema. We report the case of a patient who developed acute-onset hyponatraemia that progressed rapidly to serious neurologic...

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Detalles Bibliográficos
Autores principales: Kirpekar, Vivek C., Joshi, Prashant P.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2005
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918297/
https://www.ncbi.nlm.nih.gov/pubmed/20711296
http://dx.doi.org/10.4103/0019-5545.55960
Descripción
Sumario:Selective serotonin reuptake inhibitors (SSRIs) can cause the syndrome of inappropriate antidiuretic hormone secretion (SIADH). SIADH is associated with hyponatraemia without oedema. We report the case of a patient who developed acute-onset hyponatraemia that progressed rapidly to serious neurological dysfunction shortly after the introduction of citalopram. All SSRIs including citalopram should be used with care in the elderly. The water and electrolyte balance should be monitored carefully during SSRI therapy.

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