Ceftriaxone-induced up-regulation of cortical and striatal GLT1 in the R6/2 model of Huntington's disease

BACKGROUND: Huntington's disease (HD) is an inherited neurodegenerative disorder characterized by cortico-striatal dysfunction and loss of glutamate uptake. At 7 weeks of age, R6/2 mice, which model an aggressive form of juvenile HD, show a glutamate-uptake deficit in striatum that can be rever...

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Detalles Bibliográficos
Autores principales: Sari, Youssef, Prieto, Anne L, Barton, Scott J, Miller, Benjamin R, Rebec, George V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918547/
https://www.ncbi.nlm.nih.gov/pubmed/20663216
http://dx.doi.org/10.1186/1423-0127-17-62

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918547/
https://www.ncbi.nlm.nih.gov/pubmed/20663216
http://dx.doi.org/10.1186/1423-0127-17-62

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