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Ceftriaxone-induced up-regulation of cortical and striatal GLT1 in the R6/2 model of Huntington's disease

BACKGROUND: Huntington's disease (HD) is an inherited neurodegenerative disorder characterized by cortico-striatal dysfunction and loss of glutamate uptake. At 7 weeks of age, R6/2 mice, which model an aggressive form of juvenile HD, show a glutamate-uptake deficit in striatum that can be rever...

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Detalles Bibliográficos
Autores principales:	Sari, Youssef, Prieto, Anne L, Barton, Scott J, Miller, Benjamin R, Rebec, George V
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918547/ https://www.ncbi.nlm.nih.gov/pubmed/20663216 http://dx.doi.org/10.1186/1423-0127-17-62

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