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Hypoxia and hypoglycaemia in Ewing's sarcoma and osteosarcoma: regulation and phenotypic effects of Hypoxia-Inducible Factor

BACKGROUND: Hypoxia regulates gene expression via the transcription factor HIF (Hypoxia-Inducible Factor). Little is known regarding HIF expression and function in primary bone sarcomas. We describe HIF expression and phenotypic effects of hypoxia, hypoglycaemia and HIF in Ewing's sarcoma and o...

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Detalles Bibliográficos
Autores principales:	Knowles, Helen J, Schaefer, Karl-Ludwig, Dirksen, Uta, Athanasou, Nicholas A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918574/ https://www.ncbi.nlm.nih.gov/pubmed/20637078 http://dx.doi.org/10.1186/1471-2407-10-372

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