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Liposomal delivery of p-ialB and p-omp25 DNA vaccines improves immunogenicity but fails to provide full protection against B. melitensis challenge

BACKGROUND: We have previously demonstrated protective efficacy against B. melitensis using formulations of naked DNA vaccines encoding genes ialB and omp25. The present study was undertaken to further understand the immune response generated by the protective vaccination regimens and to evaluate ca...

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Detalles Bibliográficos
Autores principales:	Commander, Nicola J, Brewer, James M, Wren, Brendan W, Spencer, Stephen A, MacMillan, Alastair P, Stack, Judith A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918601/ https://www.ncbi.nlm.nih.gov/pubmed/20637091 http://dx.doi.org/10.1186/1479-0556-8-5

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