Cargando…

Management of Enteropathy-Associated T-Cell Lymphoma: An Algorithmic Approach

Perforation of the small intestine is the most lethal complication following induction chemotherapy for enteropathy-associated T-cell lymphoma (EATL). We report a case of EATL with a near perforated jejunal ulcer, and suggest a novel approach towards its management. Surgical resection followed by ag...

Descripción completa

Detalles Bibliográficos
Autores principales: Babel, Nitin, Paragi, Prakash, Chamberlain, Ronald Scott
Formato: Texto
Lenguaje:English
Publicado: S. Karger AG 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918827/
https://www.ncbi.nlm.nih.gov/pubmed/20740143
http://dx.doi.org/10.1159/000205183
Descripción
Sumario:Perforation of the small intestine is the most lethal complication following induction chemotherapy for enteropathy-associated T-cell lymphoma (EATL). We report a case of EATL with a near perforated jejunal ulcer, and suggest a novel approach towards its management. Surgical resection followed by aggressive chemotherapy should limit chemotherapy-associated gastrointestinal toxicity, thus allowing patients to receive adequate dose and duration of chemotherapy. The presented case highlights potential benefits of surgical intervention prior to chemotherapy for EATL.