Management of Enteropathy-Associated T-Cell Lymphoma: An Algorithmic Approach

Perforation of the small intestine is the most lethal complication following induction chemotherapy for enteropathy-associated T-cell lymphoma (EATL). We report a case of EATL with a near perforated jejunal ulcer, and suggest a novel approach towards its management. Surgical resection followed by ag...

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Detalles Bibliográficos
Autores principales: Babel, Nitin, Paragi, Prakash, Chamberlain, Ronald Scott
Formato: Texto
Lenguaje:English
Publicado: S. Karger AG 2009
Materias:
Published online: February 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918827/
https://www.ncbi.nlm.nih.gov/pubmed/20740143
http://dx.doi.org/10.1159/000205183
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author Babel, Nitin
Paragi, Prakash
Chamberlain, Ronald Scott
author_facet Babel, Nitin
Paragi, Prakash
Chamberlain, Ronald Scott
author_sort Babel, Nitin
collection PubMed
description Perforation of the small intestine is the most lethal complication following induction chemotherapy for enteropathy-associated T-cell lymphoma (EATL). We report a case of EATL with a near perforated jejunal ulcer, and suggest a novel approach towards its management. Surgical resection followed by aggressive chemotherapy should limit chemotherapy-associated gastrointestinal toxicity, thus allowing patients to receive adequate dose and duration of chemotherapy. The presented case highlights potential benefits of surgical intervention prior to chemotherapy for EATL.
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spelling pubmed-29188272010-08-25 Management of Enteropathy-Associated T-Cell Lymphoma: An Algorithmic Approach Babel, Nitin Paragi, Prakash Chamberlain, Ronald Scott Case Rep Oncol Published online: February 2009 Perforation of the small intestine is the most lethal complication following induction chemotherapy for enteropathy-associated T-cell lymphoma (EATL). We report a case of EATL with a near perforated jejunal ulcer, and suggest a novel approach towards its management. Surgical resection followed by aggressive chemotherapy should limit chemotherapy-associated gastrointestinal toxicity, thus allowing patients to receive adequate dose and duration of chemotherapy. The presented case highlights potential benefits of surgical intervention prior to chemotherapy for EATL. S. Karger AG 2009-02-28 /pmc/articles/PMC2918827/ /pubmed/20740143 http://dx.doi.org/10.1159/000205183 Text en Copyright © 2009 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: February 2009
Babel, Nitin
Paragi, Prakash
Chamberlain, Ronald Scott
Management of Enteropathy-Associated T-Cell Lymphoma: An Algorithmic Approach
title Management of Enteropathy-Associated T-Cell Lymphoma: An Algorithmic Approach
title_full Management of Enteropathy-Associated T-Cell Lymphoma: An Algorithmic Approach
title_fullStr Management of Enteropathy-Associated T-Cell Lymphoma: An Algorithmic Approach
title_full_unstemmed Management of Enteropathy-Associated T-Cell Lymphoma: An Algorithmic Approach
title_short Management of Enteropathy-Associated T-Cell Lymphoma: An Algorithmic Approach
title_sort management of enteropathy-associated t-cell lymphoma: an algorithmic approach
topic Published online: February 2009
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918827/
https://www.ncbi.nlm.nih.gov/pubmed/20740143
http://dx.doi.org/10.1159/000205183
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