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Schmincke's Tumor, Carcinoma of the Base of the Tongue c T1-2, cN2c M0 – A Case Report

BACKGROUND: Lymphoepithelial tumors are the most common carcinomas of the nasopharynx. The non-differentiated tumor, also called Schmincke's tumor, is more prevalent in the African and Chinese population. The incidence of the tumor according to age peaks between 20 and 30 years of age, and afte...

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Autores principales: Merz, H., Marnitz, S., Erbersdobler, A., Goektas, O.
Formato: Texto
Lenguaje:English
Publicado: S. Karger AG 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918848/
https://www.ncbi.nlm.nih.gov/pubmed/20740163
http://dx.doi.org/10.1159/000302139
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author Merz, H.
Marnitz, S.
Erbersdobler, A.
Goektas, O.
author_facet Merz, H.
Marnitz, S.
Erbersdobler, A.
Goektas, O.
author_sort Merz, H.
collection PubMed
description BACKGROUND: Lymphoepithelial tumors are the most common carcinomas of the nasopharynx. The non-differentiated tumor, also called Schmincke's tumor, is more prevalent in the African and Chinese population. The incidence of the tumor according to age peaks between 20 and 30 years of age, and after 60 years of age. The tumor is rarely located outside of the nasopharynx. Case Report: This report is about a 73-year-old female patient diagnosed with a tumor of the base of the tongue. The histological result shows a low-grade carcinoma of the squamous epithelium, a lymphoepithelial carcinoma. CONCLUSION: Despite the tumor's rare manifestation outside the nasopharynx, one must also consider the non-differentiated carcinoma of lymphoepithelial matrix. Especially due to the well-known early tumor spreading, cervical lymph node swelling on both sides can be recognized as a possible early symptom. First-line therapy consists of primary radiation of the tumor's primary region and its lymphoid draining channels. Concomitant chemotherapy can be applied. In case of cervical tumor spreading, a neck dissection reduces the risk of local recurrence.
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spelling pubmed-29188482010-08-25 Schmincke's Tumor, Carcinoma of the Base of the Tongue c T1-2, cN2c M0 – A Case Report Merz, H. Marnitz, S. Erbersdobler, A. Goektas, O. Case Rep Oncol Published: March 2010 BACKGROUND: Lymphoepithelial tumors are the most common carcinomas of the nasopharynx. The non-differentiated tumor, also called Schmincke's tumor, is more prevalent in the African and Chinese population. The incidence of the tumor according to age peaks between 20 and 30 years of age, and after 60 years of age. The tumor is rarely located outside of the nasopharynx. Case Report: This report is about a 73-year-old female patient diagnosed with a tumor of the base of the tongue. The histological result shows a low-grade carcinoma of the squamous epithelium, a lymphoepithelial carcinoma. CONCLUSION: Despite the tumor's rare manifestation outside the nasopharynx, one must also consider the non-differentiated carcinoma of lymphoepithelial matrix. Especially due to the well-known early tumor spreading, cervical lymph node swelling on both sides can be recognized as a possible early symptom. First-line therapy consists of primary radiation of the tumor's primary region and its lymphoid draining channels. Concomitant chemotherapy can be applied. In case of cervical tumor spreading, a neck dissection reduces the risk of local recurrence. S. Karger AG 2010-03-24 /pmc/articles/PMC2918848/ /pubmed/20740163 http://dx.doi.org/10.1159/000302139 Text en Copyright © 2010 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published: March 2010
Merz, H.
Marnitz, S.
Erbersdobler, A.
Goektas, O.
Schmincke's Tumor, Carcinoma of the Base of the Tongue c T1-2, cN2c M0 – A Case Report
title Schmincke's Tumor, Carcinoma of the Base of the Tongue c T1-2, cN2c M0 – A Case Report
title_full Schmincke's Tumor, Carcinoma of the Base of the Tongue c T1-2, cN2c M0 – A Case Report
title_fullStr Schmincke's Tumor, Carcinoma of the Base of the Tongue c T1-2, cN2c M0 – A Case Report
title_full_unstemmed Schmincke's Tumor, Carcinoma of the Base of the Tongue c T1-2, cN2c M0 – A Case Report
title_short Schmincke's Tumor, Carcinoma of the Base of the Tongue c T1-2, cN2c M0 – A Case Report
title_sort schmincke's tumor, carcinoma of the base of the tongue c t1-2, cn2c m0 – a case report
topic Published: March 2010
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918848/
https://www.ncbi.nlm.nih.gov/pubmed/20740163
http://dx.doi.org/10.1159/000302139
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