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Single-Molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations
The detection of single protein molecules1,2 in blood could help identify many new diagnostic protein markers. We report an approach for detecting hundreds to thousands of individual protein molecules simultaneously that enables the detection of very low concentrations of proteins. Proteins are capt...
Autores principales: | Rissin, David M., Kan, Cheuk W., Campbell, Todd G., Howes, Stuart C., Fournier, David R., Song, Linan, Piech, Tomasz, Patel, Purvish P., Chang, Lei, Rivnak, Andrew J., Ferrell, Evan P., Randall, Jeffrey D., Provuncher, Gail K., Walt, David R., Duffy, David C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919230/ https://www.ncbi.nlm.nih.gov/pubmed/20495550 http://dx.doi.org/10.1038/nbt.1641 |
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