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A surprising new route to 4-nitro-3-phenylisoxazole

A one-pot synthesis of 4-nitro-3-phenylisoxazole has been carried out by treatment of cinnamyl alcohol dissolved in acetic acid with sodium nitrite; in addition, 4-phenyl-3-furoxanmethanol was obtained in 40% yield.

Detalles Bibliográficos
Autores principales: Hopf, Henning, Mourad, Aboul-fetouh E, Jones, Peter G
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919271/
https://www.ncbi.nlm.nih.gov/pubmed/20703384
http://dx.doi.org/10.3762/bjoc.6.68
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author Hopf, Henning
Mourad, Aboul-fetouh E
Jones, Peter G
author_facet Hopf, Henning
Mourad, Aboul-fetouh E
Jones, Peter G
author_sort Hopf, Henning
collection PubMed
description A one-pot synthesis of 4-nitro-3-phenylisoxazole has been carried out by treatment of cinnamyl alcohol dissolved in acetic acid with sodium nitrite; in addition, 4-phenyl-3-furoxanmethanol was obtained in 40% yield.
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spelling pubmed-29192712010-08-11 A surprising new route to 4-nitro-3-phenylisoxazole Hopf, Henning Mourad, Aboul-fetouh E Jones, Peter G Beilstein J Org Chem Preliminary Communication A one-pot synthesis of 4-nitro-3-phenylisoxazole has been carried out by treatment of cinnamyl alcohol dissolved in acetic acid with sodium nitrite; in addition, 4-phenyl-3-furoxanmethanol was obtained in 40% yield. Beilstein-Institut 2010-06-23 /pmc/articles/PMC2919271/ /pubmed/20703384 http://dx.doi.org/10.3762/bjoc.6.68 Text en Copyright © 2010, Hopf et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Preliminary Communication
Hopf, Henning
Mourad, Aboul-fetouh E
Jones, Peter G
A surprising new route to 4-nitro-3-phenylisoxazole
title A surprising new route to 4-nitro-3-phenylisoxazole
title_full A surprising new route to 4-nitro-3-phenylisoxazole
title_fullStr A surprising new route to 4-nitro-3-phenylisoxazole
title_full_unstemmed A surprising new route to 4-nitro-3-phenylisoxazole
title_short A surprising new route to 4-nitro-3-phenylisoxazole
title_sort surprising new route to 4-nitro-3-phenylisoxazole
topic Preliminary Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919271/
https://www.ncbi.nlm.nih.gov/pubmed/20703384
http://dx.doi.org/10.3762/bjoc.6.68
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