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Enhanced In Vivo Activity of Cefditoren in Pre-Immunized Mice against Penicillin-Resistant S. pneumoniae (Serotypes 6B, 19F and 23F) in a Sepsis Model

BACKGROUND: Specific antibodies are likely to be present before S. pneumoniae infection. We explored cefditoren (CDN) total and free values of serum concentrations exceeding the MIC (t>MIC) related to efficacy in a mice sepsis model, and the effect of specific gammaglobulins on in-vitro phagocyto...

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Detalles Bibliográficos
Autores principales:	Cafini, Fabio, Yuste, Jose, Giménez, Maria-Jose, Sevillano, David, Aguilar, Lorenzo, Alou, Luis, Ramos-Sevillano, Elisa, Torrico, Martha, González, Natalia, García, Ernesto, Coronel, Pilar, Prieto, Jose
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919394/ https://www.ncbi.nlm.nih.gov/pubmed/20706584 http://dx.doi.org/10.1371/journal.pone.0012041

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