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The Mutyh Base Excision Repair Gene Influences the Inflammatory Response in a Mouse Model of Ulcerative Colitis

BACKGROUND: The Mutyh DNA glycosylase is involved in the repair of oxidized DNA bases. Mutations in the human MUTYH gene are responsible for colorectal cancer in familial adenomatous polyposis. Since defective DNA repair genes might contribute to the increased cancer risk associated with inflammator...

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Detalles Bibliográficos
Autores principales:	Casorelli, Ida, Pannellini, Tania, De Luca, Gabriele, Degan, Paolo, Chiera, Federica, Iavarone, Ivano, Giuliani, Alessandro, Butera, Alessia, Boirivant, Monica, Musiani, Piero, Bignami, Margherita
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919403/ https://www.ncbi.nlm.nih.gov/pubmed/20706593 http://dx.doi.org/10.1371/journal.pone.0012070

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