Degradation of HER2/neu by ANT2 shRNA suppresses migration and invasiveness of breast cancer cells

BACKGROUND: In breast cancer, the HER2/neu oncoprotein, which belongs to the epidermal growth factor receptor family, may trigger activation of the phosphoinositide-3 kinase (PI3K)/Akt pathway, which controls cell proliferation, survival, migration, and invasion. In this study, we examined the quest...

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Detalles Bibliográficos
Autores principales: Jang, Ji-Young, Jeon, Yoon-Kyung, Kim, Chul-Woo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919502/
https://www.ncbi.nlm.nih.gov/pubmed/20650008
http://dx.doi.org/10.1186/1471-2407-10-391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919502/
https://www.ncbi.nlm.nih.gov/pubmed/20650008
http://dx.doi.org/10.1186/1471-2407-10-391

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