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Degradation of HER2/neu by ANT2 shRNA suppresses migration and invasiveness of breast cancer cells
BACKGROUND: In breast cancer, the HER2/neu oncoprotein, which belongs to the epidermal growth factor receptor family, may trigger activation of the phosphoinositide-3 kinase (PI3K)/Akt pathway, which controls cell proliferation, survival, migration, and invasion. In this study, we examined the quest...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919502/ https://www.ncbi.nlm.nih.gov/pubmed/20650008 http://dx.doi.org/10.1186/1471-2407-10-391 |