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The impact of temporal variability of biochemical markers PAPP-A and free β-hCG on the specificity of the first-trimester Down syndrome screening: a Croatian retrospective study
BACKGROUND: The variability of maternal serum biochemical markers for Down syndrome, free β-hCG and PAPP-A can have a different impact on false-positive rates between the 10+0 and 13+6 week of gestation. The study population comprised 2883 unaffected, singleton, spontaneously conceived pregnancies i...
Autores principales: | Tišlarić-Medenjak, Dubravka, Zec, Ivana, Šimundić, Ana-Maria, Sabolović-Rudman, Senka, Kos, Milan, Megla, Željka Bukovec |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919561/ https://www.ncbi.nlm.nih.gov/pubmed/20630069 http://dx.doi.org/10.1186/1756-0500-3-194 |
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