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Structural studies of Helicase NS3 variants from Hepatitis C virus genotype 3 in virological sustained responder and non-responder patients
BACKGROUND: About 130 million people are infected with the hepatitis C virus (HCV) worldwide, but effective treatment options are not yet available. One of the most promising targets for antiviral therapy is nonstructural protein 3 (NS3). To identify possible changes in the structure of NS3 associat...
Autores principales: | Provazzi, Paola JS, Arcuri, Helen A, de Carvalho-Mello, Isabel Maria VG, Pinho, João Renato R, Nogueira, Maurício L, Palma, Mário S, Rahal, Paula |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919562/ https://www.ncbi.nlm.nih.gov/pubmed/20630078 http://dx.doi.org/10.1186/1756-0500-3-196 |
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