Synergistic growth inhibition of anaplastic large cell lymphoma cells by combining cellular ALK gene silencing and a low dose of the kinase inhibitor U0126

Abnormal expression of anaplastic lymphoma kinase (ALK) gene is a key pathogenic factor for Anaplastic Large Cell Lymphoma (ALCL). To study the role of ALK, an inducible shRNA system was stably introduced into cultured human ALCL cells. Inducing shRNA expression in the generated cells resulted in ce...

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Detalles Bibliográficos
Autores principales: Ito, M, Zhao, N, Zeng, Z, Chang, CC, Zu, Y
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919633/
https://www.ncbi.nlm.nih.gov/pubmed/20448669
http://dx.doi.org/10.1038/cgt.2010.20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919633/
https://www.ncbi.nlm.nih.gov/pubmed/20448669
http://dx.doi.org/10.1038/cgt.2010.20

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