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Insights into the mechanism of Rad51 recombinase from the structure and properties of a filament interface mutant

Rad51 protein promotes homologous recombination in eukaryotes. Recombination activities are activated by Rad51 filament assembly on ssDNA. Previous studies of yeast Rad51 showed that His352 occupies an important position at the filament interface, where it could relay signals between subunits and ac...

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Detalles Bibliográficos
Autores principales: Chen, Jianhong, Villanueva, Nicolas, Rould, Mark A., Morrical, Scott W.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919713/
https://www.ncbi.nlm.nih.gov/pubmed/20371520
http://dx.doi.org/10.1093/nar/gkq209