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The role of the universally conserved A2450–C2063 base pair in the ribosomal peptidyl transferase center

Despite the fact that all 23S rRNA nucleotides that build the ribosomal peptidyl transferase ribozyme are universally conserved, standard and atomic mutagenesis studies revealed the nucleobase identities being non-critical for catalysis. This indicates that these active site residues are highly cons...

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Detalles Bibliográficos
Autores principales:	Chirkova, Anna, Erlacher, Matthias D., Clementi, Nina, Zywicki, Marek, Aigner, Michaela, Polacek, Norbert
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919715/ https://www.ncbi.nlm.nih.gov/pubmed/20375101 http://dx.doi.org/10.1093/nar/gkq213

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