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DNA-binding properties of T4 UvsY recombination mediator protein: polynucleotide wrapping promotes high-affinity binding to single-stranded DNA

To carry out homologous recombination events in the cell, recombination proteins must be able to recognize and form presynaptic filaments on single-stranded DNA (ssDNA) in the presence of a vast excess of double-stranded DNA (dsDNA). Therefore recombination machineries stringently discriminate betwe...

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Detalles Bibliográficos
Autores principales: Xu, Hang, Beernink, Hans T. H., Morrical, Scott W.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919719/
https://www.ncbi.nlm.nih.gov/pubmed/20371513
http://dx.doi.org/10.1093/nar/gkq219