Cargando…
Recruitment of MBD1 to target genes requires sequence-specific interaction of the MBD domain with methylated DNA
MBD1, a member of the methyl-CpG-binding domain family of proteins, has been reported to repress transcription of methylated and unmethylated promoters. As some MBD1 isoforms contain two DNA-binding domains—an MBD, which recognizes methylated DNA; and a CXXC3 zinc finger, which binds unmethylated Cp...
| Autores principales: | , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919722/ https://www.ncbi.nlm.nih.gov/pubmed/20378711 http://dx.doi.org/10.1093/nar/gkq228 |