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Distinct 5′ UTRs regulate XIAP expression under normal growth conditions and during cellular stress
X-chromosome linked inhibitor of apoptosis, XIAP, is cellular caspase inhibitor and a key regulator of apoptosis. We and others have previously shown that XIAP expression is regulated primarily at the level of protein synthesis; the 5′ untranslated region (UTR) of XIAP mRNA contains an Internal Ribo...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919726/ https://www.ncbi.nlm.nih.gov/pubmed/20385593 http://dx.doi.org/10.1093/nar/gkq241 |