Nucleolin binds to a subset of selenoprotein mRNAs and regulates their expression

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Selenium, an essential trace element, is incorporated into selenoproteins as selenocysteine (Sec), the 21st amino acid. In order to synthesize selenoproteins, a translational reprogramming event must occur since Sec is encoded by the UGA stop codon. In mammals, the recoding of UGA as Sec depends on...

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Detalles Bibliográficos
Autores principales: Miniard, Angela C., Middleton, Lisa M., Budiman, Michael E., Gerber, Carri A., Driscoll, Donna M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919729/
https://www.ncbi.nlm.nih.gov/pubmed/20385601
http://dx.doi.org/10.1093/nar/gkq247

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