Using next-generation sequencing for high resolution multiplex analysis of copy number variation from nanogram quantities of DNA from formalin-fixed paraffin-embedded specimens

The use of next-generation sequencing technologies to produce genomic copy number data has recently been described. Most approaches, however, reply on optimal starting DNA, and are therefore unsuitable for the analysis of formalin-fixed paraffin-embedded (FFPE) samples, which largely precludes the a...

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Detalles Bibliográficos
Autores principales: Wood, Henry M., Belvedere, Ornella, Conway, Caroline, Daly, Catherine, Chalkley, Rebecca, Bickerdike, Melissa, McKinley, Claire, Egan, Phil, Ross, Lisa, Hayward, Bruce, Morgan, Joanne, Davidson, Leslie, MacLennan, Ken, Ong, Thian K., Papagiannopoulos, Kostas, Cook, Ian, Adams, David J., Taylor, Graham R., Rabbitts, Pamela
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919738/
https://www.ncbi.nlm.nih.gov/pubmed/20525786
http://dx.doi.org/10.1093/nar/gkq510

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