A gene on the HER2 amplicon, C35, is an oncogene in breast cancer whose actions are prevented by inhibition of Syk

BACKGROUND: C35 is a 12 kDa membrane-anchored protein endogenously over-expressed in many invasive breast cancers. C35 (C17orf37) is located on the HER2 amplicon, between HER2 and GRB7. The function of over-expressed C35 in invasive breast cancer is unknown. METHODS: Tissue microarrays containing 12...

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Detalles Bibliográficos
Autores principales: Katz, E, Dubois-Marshall, S, Sims, A H, Faratian, D, Li, J, Smith, E S, Quinn, J A, Edward, M, Meehan, R R, Evans, E E, Langdon, S P, Harrison, D J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920017/
https://www.ncbi.nlm.nih.gov/pubmed/20628393
http://dx.doi.org/10.1038/sj.bjc.6605763

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