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Basic fibroblast growth factor in the bone microenvironment enhances cell motility and invasion of Ewing's sarcoma family of tumours by activating the FGFR1–PI3K–Rac1 pathway

BACKGROUND: Ewing's sarcoma family of tumours (ESFT) is a malignant small round-cell tumour of the bone and soft tissues. It is characterised by a strong tendency to invade and form metastases. The microenvironment of the bone marrow is a large repository for many growth factors, including the...

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Detalles Bibliográficos
Autores principales:	Kamura, S, Matsumoto, Y, Fukushi, J-i, Fujiwara, T, Iida, K, Okada, Y, Iwamoto, Y
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920026/ https://www.ncbi.nlm.nih.gov/pubmed/20606682 http://dx.doi.org/10.1038/sj.bjc.6605775

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