5-Fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency

BACKGROUND: Colorectal cancer is (CRC) one of the commonest cancers and its therapy is still based on few drugs. Currently, no biological criteria are used to choose the most effective of the established drugs for treatment. METHODS: A panel of 77 CRC cell lines was tested for sensitivity to 5-fluor...

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Detalles Bibliográficos
Autores principales: Bracht, K, Nicholls, A M, Liu, Y, Bodmer, W F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920028/
https://www.ncbi.nlm.nih.gov/pubmed/20606684
http://dx.doi.org/10.1038/sj.bjc.6605780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920028/
https://www.ncbi.nlm.nih.gov/pubmed/20606684
http://dx.doi.org/10.1038/sj.bjc.6605780

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