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Effect of codon optimization and subcellular targeting on Toxoplasma gondii antigen SAG1 expression in tobacco leaves to use in subcutaneous and oral immunization in mice

BACKGROUND: Codon optimization and subcellular targeting were studied with the aim to increase the expression levels of the SAG1(78-322 )antigen of Toxoplasma gondii in tobacco leaves. The expression of the tobacco-optimized and native versions of the SAG1 gene was explored by transient expression f...

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Detalles Bibliográficos
Autores principales: Laguía-Becher, Melina, Martín, Valentina, Kraemer, Mauricio, Corigliano, Mariana, Yacono, María L, Goldman, Alejandra, Clemente, Marina
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920232/
https://www.ncbi.nlm.nih.gov/pubmed/20633272
http://dx.doi.org/10.1186/1472-6750-10-52