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Structural basis of Fic mediated adenylylation
The Fic family of adenylyltransferases, defined by a core HPFx(D/E)GN(G/K)R motif, consist of over 2700 proteins found from bacteria to humans. IbpA from the bacterial pathogen Histophilus somni contains two Fic domains that adenylylate the switch1 Tyr residue of Rho-family GTPases, allowing the bac...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920259/ https://www.ncbi.nlm.nih.gov/pubmed/20622875 http://dx.doi.org/10.1038/nsmb.1867 |