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Comparative Immunogenicity of HIV-1 Clade C Envelope Proteins for Prime/Boost Studies

BACKGROUND: Previous clinical efficacy trials failed to support the continued development of recombinant gp120 (rgp120) as a candidate HIV vaccine. However, the recent RV144 HIV vaccine trial in Thailand showed that a prime/boost immunization strategy involving priming with canarypox vCP1521 followe...

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Detalles Bibliográficos
Autores principales: Smith, Douglas H., Winters-Digiacinto, Peggy, Mitiku, Misrach, O'Rourke, Sara, Sinangil, Faruk, Wrin, Terri, Montefiori, David C., Berman, Phillip W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920315/
https://www.ncbi.nlm.nih.gov/pubmed/20711452
http://dx.doi.org/10.1371/journal.pone.0012076