Cargando…
Comparative Immunogenicity of HIV-1 Clade C Envelope Proteins for Prime/Boost Studies
BACKGROUND: Previous clinical efficacy trials failed to support the continued development of recombinant gp120 (rgp120) as a candidate HIV vaccine. However, the recent RV144 HIV vaccine trial in Thailand showed that a prime/boost immunization strategy involving priming with canarypox vCP1521 followe...
Autores principales: | Smith, Douglas H., Winters-Digiacinto, Peggy, Mitiku, Misrach, O'Rourke, Sara, Sinangil, Faruk, Wrin, Terri, Montefiori, David C., Berman, Phillip W. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920315/ https://www.ncbi.nlm.nih.gov/pubmed/20711452 http://dx.doi.org/10.1371/journal.pone.0012076 |
Ejemplares similares
-
P05-14 LB. Analysis of virus swarms to identify vaccine immunogens with improved exposure of epitopes recognized by broadly neutralizing antibodies
por: Berman, P, et al.
Publicado: (2009) -
Ancestral sequences from an elite neutralizer proximal to the development of neutralization resistance as a potential source of HIV vaccine immunogens
por: Mesa, Kathryn A., et al.
Publicado: (2019) -
Gene editing in CHO cells to prevent proteolysis and enhance glycosylation: Production of HIV envelope proteins as vaccine immunogens
por: Li, Sophia W., et al.
Publicado: (2020) -
Rapid development of cross-clade neutralizing antibody responses after clade B gp120/gp140 protein priming and clade c gp140 protein boosting
por: Spearman, P, et al.
Publicado: (2012) -
Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting
por: Cheng, Cheng, et al.
Publicado: (2019)