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Mediator of DNA Damage Checkpoint 1 (MDC1) Contributes to High NaCl-Induced Activation of the Osmoprotective Transcription Factor TonEBP/OREBP

BACKGROUND: Hypertonicity, such as induced by high NaCl, increases the activity of the transcription factor TonEBP/OREBP whose target genes increase osmoprotective organic osmolytes and heat shock proteins. METHODOLOGY: We used mass spectrometry to analyze proteins that coimmunoprecipitate with TonE...

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Detalles Bibliográficos
Autores principales:	Kunin, Margarita, Dmitrieva, Natalia I., Gallazzini, Morgan, Shen, Rong-Fong, Wang, Guanghui, Burg, Maurice B., Ferraris, Joan D.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920327/ https://www.ncbi.nlm.nih.gov/pubmed/20711462 http://dx.doi.org/10.1371/journal.pone.0012108

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