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Dietary Protein and Blood Pressure: A Systematic Review
BACKGROUND: Elevated blood pressure (BP), which is a major risk factor for cardiovascular disease, is highly prevalent worldwide. Recently, interest has grown in the role of dietary protein in human BP. We performed a systematic review of all published scientific literature on dietary protein, inclu...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920332/ https://www.ncbi.nlm.nih.gov/pubmed/20711407 http://dx.doi.org/10.1371/journal.pone.0012102 |
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author | Altorf – van der Kuil, Wieke Engberink, Mariëlle F. Brink, Elizabeth J. van Baak, Marleen A. Bakker, Stephan J. L. Navis, Gerjan van 't Veer, Pieter Geleijnse, Johanna M. |
author_facet | Altorf – van der Kuil, Wieke Engberink, Mariëlle F. Brink, Elizabeth J. van Baak, Marleen A. Bakker, Stephan J. L. Navis, Gerjan van 't Veer, Pieter Geleijnse, Johanna M. |
author_sort | Altorf – van der Kuil, Wieke |
collection | PubMed |
description | BACKGROUND: Elevated blood pressure (BP), which is a major risk factor for cardiovascular disease, is highly prevalent worldwide. Recently, interest has grown in the role of dietary protein in human BP. We performed a systematic review of all published scientific literature on dietary protein, including protein from various sources, in relation to human BP. METHODOLOGY/PRINCIPAL FINDINGS: We performed a MEDLINE search and a manual search to identify English language studies on the association between protein and blood pressure, published before June 2010. A total of 46 papers met the inclusion criteria. Most observational studies showed no association or an inverse association between total dietary protein and BP or incident hypertension. Results of biomarker studies and randomized controlled trials indicated a beneficial effect of protein on BP. This beneficial effect may be mainly driven by plant protein, according to results in observational studies. Data on protein from specific sources (e.g. from fish, dairy, grain, soy, and nut) were scarce. There was some evidence that BP in people with elevated BP and/or older age could be more sensitive to dietary protein. CONCLUSIONS/SIGNIFICANCE: In conclusion, evidence suggests a small beneficial effect of protein on BP, especially for plant protein. A blood pressure lowering effect of protein may have important public health implications. However, this warrants further investigation in randomized controlled trials. Furthermore, more data are needed on protein from specific sources in relation to BP, and on the protein-BP relation in population subgroups. |
format | Text |
id | pubmed-2920332 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-29203322010-08-13 Dietary Protein and Blood Pressure: A Systematic Review Altorf – van der Kuil, Wieke Engberink, Mariëlle F. Brink, Elizabeth J. van Baak, Marleen A. Bakker, Stephan J. L. Navis, Gerjan van 't Veer, Pieter Geleijnse, Johanna M. PLoS One Research Article BACKGROUND: Elevated blood pressure (BP), which is a major risk factor for cardiovascular disease, is highly prevalent worldwide. Recently, interest has grown in the role of dietary protein in human BP. We performed a systematic review of all published scientific literature on dietary protein, including protein from various sources, in relation to human BP. METHODOLOGY/PRINCIPAL FINDINGS: We performed a MEDLINE search and a manual search to identify English language studies on the association between protein and blood pressure, published before June 2010. A total of 46 papers met the inclusion criteria. Most observational studies showed no association or an inverse association between total dietary protein and BP or incident hypertension. Results of biomarker studies and randomized controlled trials indicated a beneficial effect of protein on BP. This beneficial effect may be mainly driven by plant protein, according to results in observational studies. Data on protein from specific sources (e.g. from fish, dairy, grain, soy, and nut) were scarce. There was some evidence that BP in people with elevated BP and/or older age could be more sensitive to dietary protein. CONCLUSIONS/SIGNIFICANCE: In conclusion, evidence suggests a small beneficial effect of protein on BP, especially for plant protein. A blood pressure lowering effect of protein may have important public health implications. However, this warrants further investigation in randomized controlled trials. Furthermore, more data are needed on protein from specific sources in relation to BP, and on the protein-BP relation in population subgroups. Public Library of Science 2010-08-11 /pmc/articles/PMC2920332/ /pubmed/20711407 http://dx.doi.org/10.1371/journal.pone.0012102 Text en Altorf - van der Kuil et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Altorf – van der Kuil, Wieke Engberink, Mariëlle F. Brink, Elizabeth J. van Baak, Marleen A. Bakker, Stephan J. L. Navis, Gerjan van 't Veer, Pieter Geleijnse, Johanna M. Dietary Protein and Blood Pressure: A Systematic Review |
title | Dietary Protein and Blood Pressure: A Systematic Review |
title_full | Dietary Protein and Blood Pressure: A Systematic Review |
title_fullStr | Dietary Protein and Blood Pressure: A Systematic Review |
title_full_unstemmed | Dietary Protein and Blood Pressure: A Systematic Review |
title_short | Dietary Protein and Blood Pressure: A Systematic Review |
title_sort | dietary protein and blood pressure: a systematic review |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920332/ https://www.ncbi.nlm.nih.gov/pubmed/20711407 http://dx.doi.org/10.1371/journal.pone.0012102 |
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